Tanshinone IIA (12) inhibited the breast cancer cell line MCF-7 growth by inhibiting the mammalian target of rapamycin (mTOR), phosphatidylinositol-3-kinase (PI3K), mitogen-activated protein kinase (MAPK) signalling pathway protein kinase B (Akt), and protein kinase C (PKC) [31]. Here, AKT1 is linked to breast cancer.