NPPB and hydrops fetalis: In a large Asian population, Yamamoto M et al. evaluated the additional clinical value of sST2, Pentraxin 3, Galectin-3, and high-sensitive cardiac troponin (hs-TnT) beyond BNP for risk stratification, showing that sST2 was associated with significant outcomes (all-cause, cardiovascular mortality, and HF hospitalization) in patients with acute decompensated HF solely in subjects with preserved ejection fraction [18].