CD8A and neoplasm: In studies of the Eo771/MUC1 GEMM TNBC, treatment with GO-203 also resulted in (i) downregulation of PD-L1 expression, (ii) activation of CD8+ T cells in the TME, (iii) induction of TILs effective in killing Eo771/MUC1 tumor cells and (iv) inhibition of Eo771/MUC1 tumor growth [94].