TGFB1 and pulmonary fibrosis: The over-production and deposition of the collagen in idiopathic pulmonary fibrosis is also due to the trans-differentiation of endothelial cells, not only of alveolar cells into myofibroblasts, and their induction is done similarly by TGF-β, Wnt/β-catenin pathways, and PDGF pathways [43].