We treated LNCaP (prostate adenocarcinoma cells) and RWPE-1 cells (normal prostatic epithelial cells) with 10 nM synthetic androgens (R1881) for 24 h and assessed gene expression of EDEM1, EDEM2 and EDEM3 (Figure 1F,G). This evidence concerns the gene EDEM2 and prostate adenocarcinoma.