IL12A and panuveitis: On the other hand, the M2-like microglia is associated with tissue repair and recovery from injury, and IL-35 regulates the M1/M2 macrophage ratio and promotes microglial M2 polarization and single nucleotide polymorphemic changes in il-12a (SNP rs2243115) correlates with susceptibility to Vogt–Koyanagi–Harada syndrome (VKH), a severe panuveitis with acute onset [33,34,35].