At the age of eight years, a glucose tolerance test was performed, showing reactive hyperinsulinemic hypoglycemia 2 h after oral administration of 1.75 g glucose/kg body weight (plasma glucose 46 mg/dL [2.55 mmol/L], insulin 10.3 mU/L, BHB 0.1 mmol/L, free fatty acids [FFA] 1.0 mmol/L). This evidence concerns the gene INS and hyperinsulinemic hypoglycemia.