It was observed that TRAF3IP2 expressed the lowest levels in HEK293T cells (Fig. 1G-I), whereas the highest expression was found in the UOK109 cell line, which was derived from cancerous tissues of a patient with NONO-TFE3 tRCC. This evidence concerns the gene TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions.