We could assess the effect of other gene variants (TCF7L2 rs7903146, WFS1 rs1801214 and 11ΒHSD1 rs4844880) that were available from our prior study [29] and including core gene variants associated with T2DM, β-cell dysfunction and visceral adiposity [20–26, 28]. This evidence concerns the gene TCF7L2 and type 2 diabetes mellitus.