The demographic data, clinical features and laboratory examinations of the two groups did not differ significantly with regards to the presenting syndrome, duration of HIV infection, duration of anti-HIV therapy, HIV stages on admission, white cell counts, neutrophil counts, platelet counts, red-cell counts, hemoglobin, CRP, ESR, Ferritin, CD4 count, ratio of CD4/CD8 and detection of EBV. This evidence concerns the gene ESR1 and HIV infectious disease.