SIX1 and cancer: As hypoxia is a key phenomenon in cancers,[18, 19, 20] and some known transcription factors critical for the Warburg effect, such as c‐Myc and SIX1, are modulated by hypoxia at the mRNA level,[8, 21] we used RNA sequencing (RNA‐seq) to identify transcription factors with unknown functions related to the inhibition of the Warburg effect in MCF7 human breast cancer cells under hypoxia or normoxia.