OVOL2‐mediated inhibition of glycolytic gene expression was not dependent on p53, a well‐known inhibitor of glycolysis, given that p53 KO in HCT116 human colon cancer cells or p53 knockdown (KD) in MCF7 cells did not affect the repression of glycolytic gene expression by OVOL2 overexpression (Figure S1B,C, Supporting Information). Here, TP53 is linked to malignant colon neoplasm.