designed nano‐puerarin to deactivate CAFs by inhibiting the ROS production, which is the key downstream mediator of the TGF‐β profibrogenic pathway.[20] In the current study, we demonstrated that the higher the stability of NPs (β NPs and γ NPs), the more they would be engulfed by macrophages within tumor tissues. This evidence concerns the gene TGFB1 and neoplasm.