In particular, endocrine changes include hypothalamic amenorrhea, a nutritionally acquired growth hormone resistance with low insulin like growth factor-1 (IGF-1), relative hypercortisolemia [3], low leptin, insulin, amylin and oxytocin [4–6], and high peptide YY (PYY) and adiponectin [7]. Here, PYY is linked to adrenal gland hyperfunction.