In fact, during the onset of T1DM, high levels of copeptin and SUA are associated with the presence of tubular injury markers, such as neutrophil gelatin–associated lipocalin (NGAL), kidney injury molecule 1 (KIM-1), chitinase 3-like 1 (YKL-40), interleukin 18 (IL-18), and monocyte chemoattractant protein-1 (MCP-1) [3]. The gene discussed is AVP; the disease is type 1 diabetes mellitus.