As the antisera elicited by Beta and Gamma spike protein mentioned above provided relatively better protection against Omicron than other variants, several Beta variant-based vaccines are already in development (COVID-19 vaccine tracker and landscape, https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines) and may be easier to use in an emergency than an Omicron-based vaccine. Here, CHMP5 is linked to COVID-19.