Lobaplatin (chemical formula: C9H18N2O3Pt), a third-generation platinum anti-neoplastic drug, also causes GSDME-mediated pyroptosis in nasopharyngeal carcinoma by activating caspase-3 and regulating the proteasomal degradation of cIAP1/2 [116]. The gene discussed is GSDME; the disease is nasopharyngeal carcinoma.