TFR2 and hemochromatosis: Rare types of hemochromatosis, usually diagnosed in referred patients, are associated with novel HFE alleles [6] or deleterious alleles in genes that encode hemojuvelin BMP co-receptor (HJV, chromosome 1q21.1), transferrin receptor 2 (TFR2, chromosome 7q22.1), hepcidin antimicrobial peptide (HAMP, chromosome 19q13.12), and solute carrier family 40 member 1 (ferroportin) (SLC40A1, chromosome 2q32.2) [7].