Of note, in this meta-analysis, were included not only studies reporting anti-PL antibodies included in the revised Sapporo criteria (LA, anti-CL, anti-β2GP I) but also anti-PL antibodies (anti-PS, anti-PC, anti-PE, anti-PI, anti-PG, anti-PA) which have gained importance for APS diagnosis in recent literature. The gene discussed is JUP; the disease is autoimmune polyendocrinopathy.