VAV1 mutations have been also found at much lower frequency in other PTCL subtypes such as anaplastic large cell lymphoma (ALCL, 2% of total cases) and cutaneous T cell lymphoma (2% of total cases) [21, 22, 23, 24, 25, 26, 27]. This evidence concerns the gene VAV1 and mature T-cell and NK-cell non-Hodgkin lymphoma.