In addition, a CXCR3 + Th17 cell (ih Th17 cells) has recently been identified in NASH, a subpopulation of pro-inflammatory Th17 cells whose cellular metabolism is characterized by increased glycolysis and exerts its pathogenic potential through the production of IL-17A, IFN-γ and TNF-α [196]. Here, TNF is linked to metabolic dysfunction-associated steatohepatitis.