SMC5 and colorectal carcinoma: We searched GEO database and analyzed the expression levels of SMC5/6 in CRC cell lines treated with different chemotherapeutic agents, including doxorubicin (GSE116441), gemcitabine (GSE116444), lapatinib (GSE116445), sorafenib (GSE116448), and topotecan (GSE116450).32