All cells were defined as malignant cells (MITF+, 21,624 cells), cancer-associated fibroblasts (CAFs; COL1A1+, 17,434 cells), T cells (CD3D+, 8322 cells), macrophages (C1QB+, 5520 cells), endothelial cells (PECAM1+, 4033 cells), neutrophils (S100A8+, 2519 cells), B cells (CD79A+, 1007 cells), epithelial cells (EPCAM+, 657 cells), and keratinocytes (KRT14+, 607 cells) (Figure 1B–E). The gene discussed is COL1A1; the disease is cancer.