TNF and rheumatoid arthritis: The results of KEGG pathway enrichment indicated that the DEGs were mainly enriched in cytokine-cytokine receptor interaction, IL-17 signalling pathway, TNF signalling pathway, and NF-kappa B signalling pathway, as well as pathways including Rheumatoid arthritis and some infective diseases, for instance, the Malaria, Pertussis, and Legionellosis.