SS has been associated with the same risk haplotypes as SLE DR2-DQ6 (DRB1*1501, DQA1*0102, and DQB1*0602) and DR3-DQ2 (DRB1*0301, DQA1*0501, and DQB1*0201) [39]. This evidence concerns the gene HLA-DRB1 and systemic lupus erythematosus.