TNFSF11 and osteoporosis: Based on our promising in vitro results, further preclinical studies should be performed to evaluate the efficacy and the absorption of the dietary product in animal models of osteoporosis such as pre-geriatric and geriatric mice [53] developing age-related osteoporosis, ovariectomized mice mimicking osteoporosis in postmenopausal women or RANKL-treated mice, which rapidly lose bone tissue [54,55].