IGF1 and obesity due to melanocortin 4 receptor deficiency: They found that 8 weeks of LJP consumption significantly decreased the total fat mass and triglycerides in body composition as well as significantly increased the serum brain-derived neurotrophic factor (BDNF), angiotensin-converting enzyme, human growth hormone, insulin-like growth factor-1 levels, and total lean mass as well as improvements in the total work, knee extension, and flexion, implying that LJP may have anti-obesity properties and increase the release of muscle-related growth hormones [49].