Recently, we found that BAFF and APRIL expressions were increased significantly in patients with asthma compared to healthy controls, and the increased expression of BAFF-r/BCMA, but not TACI receptors, was associated with the increased expression of BAFF and APRIL, which may suggest a possible increased B-cell response to BAFF and APRIL [31]. The gene discussed is TNFSF13B; the disease is asthma.