Further analysis of immune cell response as depicted by the staining of the marker CD11b, which expressed on the surface of monocytes, granulocytes, macrophages, and other cells of the innate immune system, revealed massive infiltration of CD11b+ cells in the lungs of SARS-CoV-2-infected mice at 5 days post infection (Figure 1F,G). This evidence concerns the gene ITGAM and infection.