In recent years, progress has been made in the study of the anti-cancer mechanisms of cordycepin, and many reviews show that cordycepin may facilitate tumor cell death via cysteine–aspartic proteases (caspases), mitogen-activated protein kinase (MAPK) and glycogen synthase kinase (GSK)-3β pathways mediated by putative adenosine receptors, death receptors and/or epidermal growth factor receptors (EGFR) [23,24]. The gene discussed is EGFR; the disease is neoplasm.