SIRT1 and colitis: Here, we observed that the treatment with Ulva at the dose of 50 mg/kg, even more effectively at the dose of 100 mg/kg, enhanced the antioxidant defenses by promoting Nrf2 translocation into the nucleus (Figure 7E, see densitometric analysis Figure 7(E1)) and obstacle the decrease of SIRT1 expression level, a class III NAD+-dependent deacetylase (Figure 7F, see densitometric analysis Figure 7(F1)), which had been dysregulated by DNBS-induced colitis.