THAP1 has been associated with DYT6 dystonia [18], THAP5 and THAP1 have been linked to apoptosis [19,20], the LRRC49/THAP10 bidirectional gene pair is involved in breast cancer [21], and THAP11 has been implicated in colon and gastric cancers [22,107]. This evidence concerns the gene LRRC49 and breast carcinoma.