INS and type 2 diabetes mellitus: Another use of ML models in diabetes, is reflected in the study of Kazuya Fujihara et al., (2021) who propose to develop machine learning models for decision making on the initiation of insulin treatment in Japanese patients with T2DM, their purpose is to examine the ability of machine learning models to predict the initiation of insulin use given by specialists and whether the machine learning approach could support decision making by general practitioners for insulin initiation in patients with T2DM.