In the PWAS analysis combined with the ROS/MAP proteome reference weights, a total of eight candidate genes associated with PTSD were identified, such as ADK (pPWAS-ROS/MAP = 3.00 × 10−5) in the all population; PCYOX1 (pPWAS-ROS/MAP = 2.70 × 10−4) in females; and BCAN (pPWAS-ROS/MAP = 8.14 × 10−4) in males. The gene discussed is BCAN; the disease is post-traumatic stress disorder.