Although MS’s etiology is not clear, it has been hypothesized that MS could be associated with different genetic factors, such as the major histocompatibility complex HLA-DRB1 locus, and with different lifestyle and environmental factors, including tobacco smoking, childhood obesity, low vitamin D serum levels, UV radiation, and Epstein-Barr virus infection [1,15]. Here, HLA-DRB1 is linked to myeloid sarcoma.