DRD2 and schizophrenia: In a study of body weight gain in schizophrenia patients under long-term atypical antipsychotic treatment, an association of the homozygous genotype rs4436578 (DRD2) was found with a significantly increased risk of body weight gain [p = 0.001, adjusted odds ratio = 3.36 (95% confidence interval = 1.62–7.00)] [62].