In this study, we examined the distribution of the KCNJ11 rs5219 and KCNQ1 rs2237892 and rs151290 gene polymorphisms in women with GDM and pregnant women with normal carbohydrate tolerance, to verify whether these polymorphisms were risk factors for GDM and might influence the selected clinical parameters of women with GDM and their newborns. This evidence concerns the gene KCNJ11 and gestational diabetes.