This possibility was further suggested by our previous in silico analysis of correlations of high and low MGRN1 mRNA levels and clinical data in a melanoma cohort of > 450 melanoma patients (TCGA dataset, https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga, also available through xena.ucsc.edu). This evidence concerns the gene MGRN1 and melanoma.