It is well understood that, apart from MI, the serum levels of cTnT and cTnI grow in many pathological (arterial hypertension, pulmonary artery thromboembolism (PATE), atrial fibrillation, heart failure, chronic renal failure (CRF), chronic obstructive pulmonary disease (COPD), etc.)and physiological (physical exercise, psycho-emotional stresses) conditions as well as the cardiotoxicity of drugs [21,22,23,24,25,26,27,28,29,30]. The gene discussed is TNNI3; the disease is chronic obstructive pulmonary disease.