In another study, miR-181a-1 and KAT2B mRNA were identified as a combined predictor for GC with AUC > 0.95 [28], while the expression levels of HOXC6 mRNA in patients with advanced GC (AGC) were found to be significantly higher than those in patients with early-stage GC (EGC) [29]. The gene discussed is KAT2B; the disease is gastric cancer.