SEMA4B and gastric cancer: The configured biomarker panel consisted of three mRNAs (SPINK7, PPL, and SEMA4B) and two miRNAs (miR-140-5p and miR-301a), which were all significantly downregulated in the GC group, and yielded an AUC of 0.81 (95% CI 0.72–0.89).