Moreover, expression of the majority of the genes (CACNA1H, COL1A1, COL11A1, FZD8, NGFR, SFRP2, WNT2B, and WNT5A) was associated with the ‘mesenchymal’ CMS group 4 in the TCGA (The Cancer Genome Atlas) Colorectal Adenocarcinoma dataset [42] (Figure S5). This evidence concerns the gene SFRP2 and colorectal adenocarcinoma.