Likewise, genes encoding AP-1-family transcription factors (BATF3 and JUNB), regulators of the G1-S phase cell cycle phase transition (CDK6 and CCND2), components of the JAK/STAT pathway (STAT3 and IL10RB), RNA-binding proteins (SYNCRIP and ZFP36L2), and a protein prenyltransferase subunit (PTAR1) were described as essential in adult T-cell leukemia/lymphoma (ATLL) [65]. The gene discussed is ZFP36L2; the disease is adult T-cell leukemia/lymphoma.