Table 1 shows the most significant categories for upregulated in RKIP knockdown and those negatively correlated with RKIP expression in breast cancer. The top nine categories down in the RKIP knockdown all match categories in the top 11 of the sets negatively correlated with RKIP expression. Table 2 shows the most significant categories for downregulated in RKIP knockdown and those positively correlated with RKIP expression in breast cancer. The gene discussed is PEBP1; the disease is breast cancer.