A significant increase in mean fluorescence intensity (MFI) was observed in the spleen, lungs and blood of TB-Gr1-IR700 mice compared to NTB-Gr1-IR700 and TB-IgG-IR700 mice, as shown in Figure 3b, identifying the recruitment and expansion of CD11b+Gr1+ MDSCs in the spleen and lungs of the TB group. The gene discussed is ITGAM; the disease is tuberculosis.