The overexpression of transforming growth factor β (TGF-β) and EMT-transcriptional factors (EMT-TFs), such as Zinc finger E-box binding homeobox 1 (ZEB1), Fibronectin 1, and Collagen Type 1 and Type 5, and the downregulation of MET-TFs, such as Ovo-Like Transcriptional Repressor 1 (OVOL1), in the neoplastic cells of the infiltrative front rather than the adjacent stroma, corroborated the hypothesis of a partial EMT of bud cells [17,43], as well as the downregulation of miR-200 and miR-141 of cell buds from the neoplastic central area to the infiltrative tumor front [17]. This evidence concerns the gene ZEB1 and neoplasm.