In all the articles studied, it was observed that the efficacy and usefulness of the different drugs in combating CRS were based on their ability to reduce the levels of the pro-inflammatory cytokines IL-1, IL-2R, IL-6, IL-8, IL-10, IL-18, TNF-α, and MCP-1 [35,36,37,38,39,40,41,42,43,44]. The gene discussed is IL6; the disease is congenital rubella syndrome.