CD79A and Alzheimer disease: Moreover, KEGG pathway enrichment of these hub genes revealed some immune processes/diseases, such as intestinal immune network for IgA production (hsa04672, adj.p = 5.77 × 10−43), type I diabetes mellitus (hsa04940, adj.p = 1.21 × 10−42) and inflammatory bowel disease (hsa05321, adj.p = 7.41 × 10−42), which are related to imbalance of the gut microbiota [52], and emerging evidence shows that AD may begin in the gut, and it is closely related to such an imbalance [53].