SS is characterised by a pro-inflammatory environment and cytokine profiling of serum, tears and saliva identified a predominance of pro-inflammatory cytokines, such as MIP, IL-1, IFN-γ, TNF-α, IL-6, IL-12 or IL17 in various proportions, as well as increased anti-inflammatory molecules, such as IL-4 or IL-10. Here, IL4 is linked to synovial sarcoma.