CYP7A1 and Hepatic steatosis: In regard to hepatic steatosis, Hyp attenuated the lipid accumulation in liver by preserving hepatic lipid and bile acid homeostasis via the regulation of PPARγ, FXR, LXRα, ACC, SREBP, cholesterol 7α-hydroxylase (CYP7A1), and CYP27A1.