In regard to hepatic steatosis, Hyp attenuated the lipid accumulation in liver by preserving hepatic lipid and bile acid homeostasis via the regulation of PPARγ, FXR, LXRα, ACC, SREBP, cholesterol 7α-hydroxylase (CYP7A1), and CYP27A1. This evidence concerns the gene CYP27A1 and fatty liver disease.