In SCA2, the persistence of long telomeres in leukocytes is an intriguing observation that needs to be investigated to verify whether this is due to the persistence of telomerase, as observed in ALS patients [53], or to the suppression phenomena of the immune response, as proposed for Parkinson’s disease [52], or to the activation of the alternative lengthening of telomeres (ALT) mechanism, as shown in some tumors [23] and FRDA [64]. Here, GPT is linked to Parkinson disease.