MAPT and supranuclear palsy, progressive, 1: The most common tauopathies are Alzheimer’s disease (AD) and frontotemporal lobar degeneration Tau (FTLD-Tau), which encompass a spectrum of several syndromes such as progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), Pick’s disease (PiD), and frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17).